Some of the wounded were grazed by bullets and others hit directly, but all were expected to survive, officials said.

The gunshots rang out on the Fifth Avenue side of the building at around 9 a.m., a time of day when the sidewalks around the building are packed with pedestrians and merchants were opening their shops.

After the shootout, crowds of tourists and people on their way to work gathered along 34th Street, which was shut down by police. Police helicopters buzzed overhead and swarms of officers were gathered around the crime scene.

Jeffrey Johnson, 53, was laid off about a year ago at Hazan Imports and confronted a 41-year-old former colleague, shooting the man in the head, Police Commissioner Raymond Kelly said. The two had traded accusations of harassment when Johnson worked there, he said.

Johnson walked away after shooting his ex-colleague, and a construction worker who witnessed the encounter followed Johnson and alerted police, officials said. Johnson then turned his .45-caliber pistol on the two officers and they traded gunfire, killing Johnson, Kelly said.

He apparently fired at officers, but it’s not clear how many shots, Kelly said. The two officers fired a total of 14 rounds, he said. Mayor Michael Bloomberg said some of the nine wounded may have been shot by police in the mayhem.

Johnson worked at the company near the building for about six years and was laid off because of downsizing, Kelly said.

“We were just working here and we just heard bang, bang, bang!” said Mohammed Bachchu, 22, of Queens, a worker at a nearby souvenir shop. He said he rushed from the building and saw seven people lying on the ground, covered in blood.

Queens resident Rebecca Fox, 27, said she saw people running down the street and initially thought it was a celebrity sighting, but then saw a woman shot in the foot and a man dead on the ground.

“I was scared and shocked and literally shaking,” she said. She said police seemed to appear in seconds. “It was like CSI, but it was real.”

Hassam Cissa, 22, of the Bronx, said he saw two bodies on the ground and police applying a white cloth to a man’s stomach wound.

Gunshots so close to one of the city’s leading tourist attractions immediately prompted fears of terrorism, but federal officials said that wasn’t the case, and a guard at skyscraper said it didn’t involve the parts of the building where tourists gather to visit the skyscraper.

The gunfire came less than two weeks after a knife-wielding man was shot dead by police near Times Square, another tourist-saturated part of the city. Authorities say police shot 51-year-old Darrius Kennedy after he lunged at officers with a kitchen knife Aug. 12. Kennedy was smoking marijuana in Times Square on a Saturday afternoon when officers first approached, police said. It was the beginning of an encounter that would stretch for seven crowded blocks.

In 1997, a gunman opened fire on the 86th floor observation deck of the Empire State Building, killing one tourist and wounding six others before fatally shooting himself.

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Associated Press writers Alex Katz and Samantha Gross contributed to this report.