Michelle Wolf upgraded her insults against the Trump administration and this time likened Ivanka Trump to a nasty, incurable disease and urged people to heckle Trump in the worst way on her Netflix show.

As Trump officials call for civility after Sarah Huckabee Sanders was verbally slammed, put out and refused service at a Red Hen restaurant, Wolf urged viewers of her new show, The Break, to instead double-down on the insults.

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“You have to make sure your words are life-alteringly hurtful. You gotta hit their deepest insecurities with the hot venom of a teenager from a broken home,” she said.

She then took aim at Trump’s daughter and White House senior advisor Ivanka Trump.

“Then, talk to her in terms she will understand,” Wolf continued. “Say, ‘Ivanka, you’re like vaginal mesh. You were supposed to support women, but now you have blood all over you and you’re the center of a thousand lawsuits. (You’re) like that birth control pill Yaz, at first it seemed like it’d be really cool and helpful, but you need to be immediately recalled.”

Michelle Wolf continued: “Is your nickname herpes?” she asked Ivanka.

“Because you’re not necessarily the most dangerous person in the administration but you’re very unpleasant, totally incurable and you always show up when we’re about to get (expletive).”

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The insults were true to Wolf’s style. The comedienne became internet famous after she delivered a hilarious blistering of the Trump Administration, the White House Press Corps, and particularly, White House Press Secretary, Sanders at the White House Correspondent’s dinner.

“If you see Ivanka on the street, first call her ‘Tiffany.’ This will devastate her,” Michelle Wolf said.